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Picosecond dual-wavelength
fiber-based laser source for Guangzhou CCELAB
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It took a lot of heart and sweat, but now it's done: WinWinTec
International Group and TRUMPF Active Fiber Systems have won a
bidding competition from a southern Chinese research group to
develop a dual-wavelength picosecond fiber laser for Stimulated
Raman Scattering (SRS) microscopy.
With the SRS laser, we address a tunability range from 1000 to
3300 cm-1 with a spectral bandwidth of <10cm-1
(output 1) and <15cm-1 (output 2), respectively. For
our users, which are researchers from the Zhongshan School of
Medicine, Sun-Yat-Sen University, and the Chemistry and Chemical
Engineering Guangdong Laboratory, we will integrate it into a
general-purpose SRS microscope to achieve rapid chemical mapping
in biological materials and pharmaceuticals. Furthermore, the
SRS laser will be used for developing SRS tags for medical diagnosis.
Our SRS lasers involve third-order nonlinear optical processes
where three electromagnetic waves interact with the sample volume
to generate a characteristic optical signal. Upon coincidence
of the difference frequency of a pair of such waves corresponding
to the frequency of a Raman resonance, the signal is greatly enhanced.
These techniques are typically employed to image bio-molecules
in living or fixed cells or tissues. They offer the great advantage
to not require any sort of labeling or staining. Additionally,
spectral information is obtained using broadband light sources.
The signal-to-noise ratio of these applications benefits greatly
from the application of pulsed lasers at high repetition rates.
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